New cases of prototropic tautomerism in substituted pyridines
نویسندگان
چکیده
منابع مشابه
Tetrabutylammonium bromide-Cesium carbonate: new reagent system for the synthesis of substituted pyridines at room temperature
The highly substituted pyridine derivatives are found to exhibit diverse pharmacological activities. They are also emerged as potential medicinal leads in developing therapeutic agents for the treatment of various diseases. In this work, a series of 2-amino-3,5-dicarbonitrile-6-thio-pyridine derivatives have been synthesized at room temperature via one-pot, multi-component reaction of various a...
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NMR methods have been applied to evaluation of prototropic tautomerism, N (1)H ^ N (3) H. in several selected pyrimidines, viz. the neutral forms of isocytosine and 2-alkylthiopyrimidone-4, and the monoanionic forms of uracil, 5-fluorouracil and 4-thiouracil. The predominant tautomeric species of the neutral forms could be estimated only qualitatively from chemical shifts. For the monoanionic f...
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In this study we report about two novel azomethine–BODIPY dyads 1 and 2. The two dyads have been, respectively, synthesized by covalent tethering of tautomeric ortho-hydroxy aromatic azomethine moieties including N-salicylideneaniline (SA) and N-naphthlideneaniline (NA) to a BODIPY fluorophore. Both of the two dyads 1 and 2 show enol-imine (OH) structures dominating in the crystalline state. Dy...
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Multiconfigurational, intermediate valent ground states are established in several methyl-substituted bipyridine complexes of bis(pentamethylcyclopentadienyl)ytterbium, Cp2*Yb (Me(x)-bipy). In contrast to Cp2*Yb(bipy) and other substituted-bipy complexes, the nature of both the ground state and the first excited state are altered by changing the position of the methyl or dimethyl substitutions ...
متن کاملDFT studies on tautomerism of C5-substituted 1,2,3-triazoles
DFT (B3PW91/6-311þþG**), ab initio (HF/6-311þþG**), and single point CCSD(T)/6-311þþG**//B3PW91/6311þþG** calculations were performed to investigate the stability and tautomerism of the C5-substituted 1,2,3-triazoles. Three different tautomers are possible for the substituted 1,2,3-triazoles: N1–H, N2–H, and N3–H. For all the substituents applied, the most stable is the N2–H tautomer. Out of th...
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ژورنال
عنوان ژورنال: Journal of Chemical Engineering And Bioanalytical Chemistry
سال: 2017
ISSN: 2575-5641
DOI: 10.25177/jcebc.1.1.5